Dihydropyrimidinethione

3,4-Dihydropyrimidine-2(1H)-thione





Reference:
J. Med. Chem. 2025, 68, 24869–24889.
The detailed experimental procedures can be found in the freely accessible Supporting Information.

1,4-Dihydropyrimidine

Reference:
J. Med. Chem. 2025, 68, 24869–24889.

The detailed experimental procedures can be found in the freely accessible Supporting Information.

Imidazole

1H-Imidazole





Reference:
J. Med. Chem. 2025, 68, 25844-25865.

The detailed experimental procedures can be found in the freely accessible Supporting Information.

Imidazopteridinone

Imidazo[1,2-f]pteridin-6(5H)-one





Reference:
J. Med. Chem. 2025, 68, 25844-25865.

The detailed experimental procedures can be found in the freely accessible Supporting Information.

Oxadiazole

1,2,4-Oxadiazole





Reference:
J. Med. Chem. 2021, 64, 14142–14152.

Pyrazolopyridine

1H-Pyrazolo[4,3-c]pyridine





a.t.: ambient temperature
The second reaction was carried out under argon atmosphere (Ar atm.).

Reference:
J. Med. Chem. 2025, 68, 5097-5119.

Indole

1H-Indole

Reference:
J. Med. Chem. 2021, 64, 1, 417–429.

The detailed experimental procedures can be found in the freely accessible Supporting Information.

Pyrrolopyridine

2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-3-ol





Reference:
J. Med. Chem. 2021, 64, 1, 417–429.

The detailed experimental procedures can be found in the freely accessible Supporting Information.

Imidazopyridazine

Imidazo[1,2-b]pyridazine





Reference:
J. Med. Chem. 2025, 68, 21982-21916.

Pyrrolotriazole

6,7-Dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole





Reference:
J. Med. Chem. 2025, 68, 23050-23077.