Pyrrolo[1,2-a]quinoxalin-4(5H)-one

Route 1

Reference:
1.    Biorg. Chem. 2022, 126, 105860.

Route 2

Reference:
1.    J. Med. Chem. 2004, 47, 1997-2009.

Route 3

Reference:
1.    J. Med. Chem. 1997, 40, 3670-3678.

Pyrrolo[1,2-a]quinoxaline

Pyrroloquinoxaline

Reference:
1.    Eur. J. Med. Chem. 2013, 65, 205-222.

Isoquinolone

Isoquinolin-1(2H)-one

Lithiated-toluamide benzonitrile cycloaddition

Reference:

1.    Eur. J. Med. Chem. 2018, 143, 200-215.